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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1bc3ae8d5974c8101c8c908633b60faf9cbfd9e1628bb1f50b5aa886271f26' 
  AND token = '9KiMMGiK/jT8biQiLyZrEdY9dQhsXNWhUYMIOqItrHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}