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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65264187653f0796a91ea67d226da9f962d41fc07d486e67105b4cf334ff3bc' 
  AND token = 'tH5MiysEVbYTWsL++JDbfNdaXV7yTTmdxS1B13KkvmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00090

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}