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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2833b20f7f0b4e88d0a5f067b50ad8e1f85911528e7398864bec9aa3c2dc433' 
  AND token = '+Qs8aWpIdA7yKN55NryLaYPKP4nCHZdGOtXVHxinHcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}