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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164f8be605e26512682417fcc08f1b1db0db59ca4f2523f318d84b3fa21a138c' 
  AND token = 'INZeEKnMUtb4R3+XEdeibR1XEW2PMDYYsw7XRMenzjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}