SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c008586d453769aefd738be27552f3ca28a59df08a2b41344b106f7f7ae3e392' 
  AND token = 'VQHo2w0dTOKhzY4SwxRrU1MnHQym2cGJNSDt5jM8nH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}