SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7a44324b47447b55a0d55672d735f4171bbcd54a3dfbf39840ec6adc1a269d8' 
  AND token = 'BzMEEkLhV26o+OYyBDwpo0Cb5gtTbit3YutsXDhc5CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}