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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1435b84a0aea3f3577f78f6ee0e24569df099cdde78db09e9ecb976379d1b478' 
  AND token = 'c281Yqvzs5h4xKtUcwSOE1ACyJs+tDmaV5L97hBnvXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}