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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a2da0ee19afed70c84e7acf5cda06d9a43c2670d8b7a594abb6278fbc358a42' 
  AND token = 'CcORGtTMi8uZU9sfJmAIM3aGtLh0HZ8TKaxlnR05eiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}