SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4e6b5c456cb8e2d12482264adf5043bd52907eaf7320115e8ee1c844838dc51' 
  AND token = 'TwnCp47K2op2rfQMLFO9FPWhk3rUPtG0IfH93XJ5WKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}