SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d966b22215c5a0e905bbaf23fbdd31b9b90d44be1d03143c6124f994c93d81e' 
  AND token = 'A1q/cJrlEfmQujNwJhv1EUseZWQBbOaMFz515IrZqb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}