SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c0ac3837ced9715dbc28d2ab39cbefabb55eafc0cddce762f0431efb580775d' 
  AND token = 'QpYN2tuggm/icQhYZr6OjkgXSV+YHWGv/k4Gk5UxfzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}