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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d2a3feae85ebe492e47c4d0b45d12ae9207c9bcd6c0cb7c631545c483026071' 
  AND token = 'L/6O/2wll3xE3RNxQ9GGAVdplgWpdo5N2rGXXT/rDZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}