SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd5765749f3345c64727876a322f8427d1f82cff9740ca7c3643019d79a62b1c' 
  AND token = 'biBu3I09EAcsQag5m+cmTF1iMLUu+inaZRbOc92e2Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}