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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b597fb859a5f7e53248558f44456b93396a9c109f8e83755bf270b7b859c86' 
  AND token = '2fNmSKCJNxCX+S2OeTbMA6EJ7wXQnfXPX4QehNhUqhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}