SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e456e758130932e565dba7c6d274fd63c9211b303eeadf01ddb4009a72f1cb3a' 
  AND token = 'hboHjURf2BPFbpZ0fYJSak6Qb3uuUPgjJo1X/U4xnCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}