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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e24d99ff077589fcc0c3cc99a97e1ba375ea0648425f1e725ff1c4bb530b500' 
  AND token = 'doxjcFf9JjaUQJjCe06vIhX6yi6SAlWzrYeddlFbok4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}