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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f805c324b875b5f3e8d8abdee09e02d5922e7e2e06a34df4d78c6c35517c6e53' 
  AND token = 'NpEWs0W8ABWIzpSLUQP+hPwMGLfTfxNDjMtken5CLn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}