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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0acd54426a3584eba4eadf8bc80780314d8ea14f20a8b63b8556c624b07ac6a9' 
  AND token = 'l8QcB6C9aynK+o0zomcf0Equ8ZdkNCRI8IVPtzMcJAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}