SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0794b573f48d9f059f4c8bc978d02c45aeb80404d806bad03f2f89d213933a' 
  AND token = 'aZjS+qg5d9f3GydkPSZae0B/JgB0RMBNXfkXJfTHCcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}