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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8da80df340d5ba7bcdc1a4b1a11517b7309412d5a6f31f41804b6a92b23b26' 
  AND token = 'qjaweM0VpXvLKKXxk0TSAgmnK2fmOlM1fnejb/dbeYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}