SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2c8d7689a4cc9ba032990130114216a0083a3d1b3a0730f728a677aa06730e' 
  AND token = 'tTPYp6vkURuG0f/0ewi6qCP6OidmBTWLtt0MqtorFKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}