SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95080adda0d42b06c0f1b8f2dd5060e5dff52888cfc91c06339d4e8f9c74613d' 
  AND token = 'hAHZ/VzjYDaMLPPI00oBSc8LqJtKvAd6Crm5j6tUw9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}