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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01964b4d8814fc56610e1cc002056d9b427b82a98f68124be36e3c326b19f122' 
  AND token = 'rO8/KiBvxnw5ZuRMLS4P+yNOlct7oS9E7K7pCCSluRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}