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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0eecbbef2f993273e56c8a15b249f5421de38b7f3c70aa839f7e06e615140b' 
  AND token = '+Ql2wFGLzl9mUNNeQiw0Mfa2FrKz1eCv3aljC8lg5Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}