SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66e0d642ecb91cdfe251b7698a01196cba18b139b7c71303b5cb0c40afbde9b' 
  AND token = 'peIr7gUOlEYIXVW/vf3LgHSAByTImSD4Vtojh/bt0Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}