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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d667ffc49b9809ca2154761977c22a006e92740f341fac795d377efd1fab614' 
  AND token = 'Ra1BIaw4LSwR29OtqGcgn6fSBzKCAFs6kJEpL019IPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}