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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b555c27d9a9cc532f48ec45c0b384f7616d91198fca8b07f3dc552f8c0a7ab27' 
  AND token = '2Ut+FR/tsasUtxWD6WnYacjVpvhqgnutni8dSX5eOPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}