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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a81f9d41ebd4401fda4559e7626030e459822108037956a75fa6d0277b78af' 
  AND token = '972kDsKZeZ+hOM9UXYxpouJWxEYQYdiaUeR3CNkd1Ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}