SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed0d5c86f6357e24e2230b3e1f6684297fa628193e7ca56c11755586390ddfe' 
  AND token = 'uC7myntTigtzkx0vFlXxAHg6pKkbgnBInw1cnPjzpPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}