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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b25d21ae10a7ccaf39c1a94e3869e6668f36e0dfaf7fce08a870baab9a22cf3' 
  AND token = 'jXzaFXY1DFCvHl3xLWL/f7ALc/oKj4J/WIlJ2j0lTsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}