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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3890cd990e207d984c169735bc27e4c0eb440892934e6722f8934d90445c39' 
  AND token = 'k46MiAdPdbNeFrWRqN0ncc9+KC4X0QYQ1cwXG5RsF+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}