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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eff31ac5b6486959423dbdd7f734a54c84602c619722bd163b4d255b3382000' 
  AND token = 'fPHn4WUeW2t/7CeTjgQkZC/jWFEY4uHE+ma6r0sMIiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}