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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eded5d03f388e3fe783db495db9f090dab6f113b58f2652f5e1d1feb6f4aa06' 
  AND token = 'yGLVZ8IzVBRx4nz4e/WCutXfGdKg4m0KghwDygKXZgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}