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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acf6dd4b15f8deef458cf70b8a3e7544ce25c121b9d16a11531934ca9768a2a7' 
  AND token = 'uZPF5G3MocqdpQKQ0cJj0h/z7ycDG5zfkzxKLr3tHXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}