SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8dbaa570eff31ebaa3b5f56e8e5c334d307b4cfe39caf0e67a77c897906c9de' 
  AND token = 'tR+Ma82eJfHdx7Eyr82SJw++UYxDzauZ2sLHWG8ogrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}