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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a339fbc75ff6a6ac342c71061ae3382ff0f00e7573bfd671cfa6e14d940d352d' 
  AND token = 'hqhCTdAyF48IxJlbW7YcZHw3qCFvuo+x/WH4dr4sFQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}