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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b082568d05a6ed712da43a5e2f088a63b7f1511d8fe13201b52bf3ddbac24297' 
  AND token = 'Q7Hw7zuld3eNi0aTYbCbtd+o68LXMNsRF/7yc+VRULg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}