SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f8ce1f2b1e44084b3010d66e2f8eeb1e2e4d904d3eef41bd7675d0ec911459' 
  AND token = 's35Kj5fVjBYM2Hy/6uh/RWcaTSheMi2q+ppu/evrWyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}