SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb50485ccc771371f18bb413d859d6b6cce4ac578fb11f07e71c33329fc1b943' 
  AND token = 'M/JheSw1J3u0YyQnDh2JIHM538ST/hYaekT1fz5oQVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}