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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef47b5350a2a7c96f6a0d6e80bd2fbb0083dfbced7a2a4cd0f2e763e912023f' 
  AND token = 'LdPmOY3OKtDAU2XmYcYqCMgpJnh0RA28H2qReh4Ie5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}