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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03989a8d43e955a01df9a2157029bc8e4f73349a4fdd2205c3cb7ae3d45e336' 
  AND token = 'S1GvxQ0UQzxg2zEP16IbmFvWB4lWFW8oXSkQqKAjh6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00345

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}