SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be5980c5e9f59709fb748aa614d7eb835e0d1e7a6460e65d47bd575ddb6cc70' 
  AND token = 'O+6ekZxn+0hxgm6GHWu0zweRlSDwUMxMQcoKjfQC5rU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}