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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961084ae290a778b50c7be1bb2932f5b974e7eff0cad8ce0a555f2af929afd0f' 
  AND token = 'vg6o7vYpSlDOoTVUO286pjR878zKOomr19zTp/NhF2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}