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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75141e3d087067edcadab15b555f888614a1c77e5877f8daec06e545d22cf536' 
  AND token = 'Lkayoa3QTCWAMCFDzjRR7ZWaIrkxi/GTrJMUYbjm1Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}