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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75374a7b96cdd2983b17e17d096b377aa584c954ae01932dfc13ba164a39b2c5' 
  AND token = 'mXNK1dXTp5CIkgo/ZqzVipg0NLny/hw51nx6EBon/Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}