SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56874854e4cf2c07a920d7ef4364506a974e9281463288ae930f4db9e5a9e454' 
  AND token = 'poK7m40XQjj6LYq+s5TIbb8130K+NeArRnq2+4nXtfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}