SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e881795aaf0593ebf450df1f198641741df32be6a1ba18fc33e62366318ee38c' 
  AND token = 'WSI3nME4ZvhJ9qCbBzunqL5hQCRruaMaVvOfs3JCnsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}