SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '223ea526a1a98f23766d6798b08338b0f3e4f49da633fe053c573bed7cb03453' 
  AND token = 'ao0YeUeUr656+YWOSpm3FLfPdxe4GPG9Knd7E3Dj6RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}