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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4139ff1fba1a96ec97bc913ed46d134b7cb921a1e8aebe44169c1e9c231613' 
  AND token = 'qGLRqi4VLDbCK5RZAKj+IKHBix/nEF+qRUuKAMRiqIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}