SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '358bcdd32df8d2655490f4707da8f4a1a2f23d5c0eadc19753344e70eb9794e0' 
  AND token = 'a4plQq5kZsv+sSj21w4/YioUfjqdcDUJcQ9mFzSIWR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}